BEST4: Discovering ways to find and prevent heartburn-related health problems

BEST4 is running two trials to discover ways to find heartburn-related health problems and prevent oesophageal cancer:

The BEST4 Screening Trial will be offering 40,000 people with heartburn, indigestion, or acid reflux the capsule sponge test. This is to see if the test can help find heartburn-related problems earlier and improve long-term health. This trial is planned to start in summer 2024.

The BEST4 Surveillance Trial is looking to see if the capsule sponge test can find signs of cell changes in people with Barrett’s Oesophagus. If the test works, it could be used in Barrett’s surveillance to reduce the number of endoscopies needed. 

More about the BEST4 Surveillance Trial.